180 Life Sciences To Launch $425M Ethereum Treasury, Rebrands to ETHZilla

The biotech firm 180 Life Sciences has rebranded as ETHZilla amid plans to launch an Ethereum treasury worth $425 million. The initiative will see the company use Ethereum as a core treasury asset and a standard for on-chain financial strategies.

180 Life Sciences Unveils Ethereum Treasury Plans

According to the press release, the $425 million private placement (PIPE) deal is set to close around August 1, 2025. The transaction involves the issuance of common stock at the price of $2.65 per share, with the capital raised going into the purchase of Ethereum.

Over 60 investors joined the deal, including Harbour Island, Electric Capital, Polychain, and leaders from Lido, Eigenlayer, and Compound. Following the rebranding, ETHZilla will use Ethereum as the core of its treasury reserve, similar to SharpLink Gaming. SharpLink currently holds 438,190 ETH after its latest purchase.

ETHZilla will also work closely with top DeFi projects through a strategic council. Electric Capital will serve as ETHZilla’s external asset manager. It plans to implement an on-chain yield strategy that combines ETH staking, lending, liquidity provisioning, and private DeFi agreements. The goal is to outperform standard Ethereum staking yields while managing risk carefully.

The firm also received approval to raise an additional $150 million through debt securities. That offering is expected to follow once the equity deal is complete. ETHZilla’s management team will remain in place after the rebranding.

Executives say the move will give investors exposure to Ethereum’s growing role in the stablecoin and tokenized asset markets. ETHZilla will aim to become a public benchmark for on-chain Ethereum treasury strategies.

Etherealize, a new DeFi venture, will partner with ETHZilla and help shape its treasury deployment. Its team includes builders behind some of Ethereum’s most-used protocols.

ETHZilla says it will be a community-centric vehicle built to advance Ethereum’s ecosystem while creating returns for shareholders. The company plans to file for public registration of shares after the private sale. Until then, the shares will not be available for public trading under U.S. securities laws.

The Ethereum price is trading at $3,770.65 with a slight 0.22% gain in the past 24 hours. Ethereum’s 24-hour trading volume is up by 1.19%, hitting $36.25 billion across global exchanges.